Product Description

The following is the introduction of WS 12.

Product Detail

WS 12 Basic information


Product Name:

WS 12

CAS:

68489-09-8

MF:

C18H27NO2

MW:

289.416

EINECS:


Product Categories:


Mol File:

68489-09-8.mol



WS 12 Chemical Properties


Boiling point 

447.8±28.0 °C(Predicted)

density 

1.029±0.06 g/cm3(Predicted)

FEMA 

4681 | (1R,2S,5R)-N-(4-METHOXYPHENYL)-5-METHYL-2-(1-METHYLETHYL)CYCLOHEXANECARBOXAMIDE

storage temp. 

Store at -20°C

solubility 

DMSO: >20mg/mL

form 

White to off-white powder.

pka

14.18±0.70(Predicted)

color 

white to off-white

JECFA Number

2079

InChIKey

HNSGVPAAXJJOPQ-XOKHGSTOSA-N


WS 12 Safety Information


Hazard Codes 

N

Risk Statements 

50

Safety Statements 

53-61

RIDADR 

UN 3077 9 / PGIII


WS 12 Usage And Synthesis


Chemical Properties

WS 12 is a odorless white crystalline solid,mp 178 °C, displaying a strong initial cooling effect and a long-lastingness. It is used particularly is oral care flavors.

Trade name

Winsense WS-12 (Renessenz)

Biological Activity

Potent TRPM8 agonist that acts as a cooling agent (EC 50 = 193 nM).


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