Dimethyl Sulfide

Product Name:

Dimethyl sulfide

Synonyms:

Dimethyl sulfide( 99%, HyDry, Water≤50 ppm (by K.F.));Dimethyl sulfide( 99%, HyDry, with molecular sieves, Water≤50 ppm (by K.F.));fide;methanethiomethane;Methyl Monosulfide;methylmonosulfide;Sulfide, methyl-;Sulfure de methyle

CAS:

75-18-3

MF:

C2H6S

MW:

62.13

EINECS:

200-846-2

Product Categories:

Sulfides flavors;Allium cepa (Onion);Allium sativum (Garlic);Building Blocks;Chemical Synthesis;Nutrition Research;Organic Building Blocks;Phytochemicals by Plant (Food/Spice/Herb);Sulfides/Disulfides;Sulfur Compounds;Bioactive Small Molecules;Cell Biology;DIG-DY;Amber Glass Bottles;Organics;sulfide Flavor;Reagent;Solvent Bottles;Solvent Packaging Options;Solvents;solvent

Mol File:

75-18-3.mol

Melting point 

−98 °C(lit.)

Boiling point 

38 °C(lit.)

density 

0.846 g/mL at 25 °C(lit.)

vapor density 

2.1 (vs air)

vapor pressure 

26.24 psi ( 55 °C)

FEMA 

2746 | METHYL SULFIDE

refractive index 

n20/D 1.435(lit.)

Fp 

−34 °F

storage temp. 

2-8°C

solubility 

Miscible with alcohols, ethers, esters, ketones, aliphatic and aromatic hydrocarbons. Slightly miscible with

form 

Liquid

color 

Clear colorless

Specific Gravity

0.849 (20/4℃)

Odor

Ethereal, permeating; disagreeable; offensive.

Odor Threshold

0.003ppm

explosive limit

2.2-19.7%(V)

Merck 

14,6123

JECFA Number

452

BRN 

1696847

Stability:

Stable. Incompatible with strong oxidizing agents. Highly flammable - note low boiling point, low flash point, and wide explosion limits. Mixtures with air are potentially explosive. Incompatible with strong oxidizing agents. Use in UK regulated by LPG Regulations 1978 in accordance with HSE guidance note CS17.

InChIKey

QMMFVYPAHWMCMS-UHFFFAOYSA-N

CAS DataBase Reference

75-18-3(CAS DataBase Reference)

NIST Chemistry Reference

Dimethyl sulfide(75-18-3)

EPA Substance Registry System

Dimethyl sulfide (75-18-3)

Hazard Codes 

F,Xn,Xi

Risk Statements 

11-22-37/38-41-36

Safety Statements 

7-9-16-29-33-36/39-26

RIDADR 

UN 1164 3/PG 2

WGK Germany 

1

RTECS 

PV5075000

F 

13

Autoignition Temperature

402 °F

TSCA 

Yes

HS Code 

2930 90 98

HazardClass 

3

PackingGroup 

II

Hazardous Substances Data

75-18-3(Hazardous Substances Data)

Toxicity

LD50 orally in Rabbit: 535 mg/kg LD50 dermal Rabbit > 5000 mg/kg

Description

Methyl sulfide has an unpleasant odor of wild radish that is cabbage- like. It can be tolerated as a green vegetable note only at very low levels (0.1 - 3.0 ppm). It may be produced by reaction of potassium sulfide with methyl chloride in methanol solution; from potassium methyl sulfate and potassium sulfide.

Chemical Properties

Methyl sulfide has an intense, unpleasant odor, wild radish, cabbage-like. It can be tolerated as a green vegetable note only at very low levels (0.1 to 3.0 ppm

Chemical Properties

Clear colorless liquid

Uses

Sulfiding agent.

Definition

ChEBI: A methyl sulfide in which the sulfur atom is substituted by two methyl groups. It is produced naturally by some marine algae.

Preparation

By reaction of potassium sulfide with methyl chloride in methanol solution; from potassium methyl sulfate and potas[1]sium sulfide

Aroma threshold values

Detection: 0.3 to 10 ppb. Aroma characteristics at 0.5%: sulfureous, dimethyl sulfide, creamy, tomato, fishy, scallop, berry fruity and vegetative nuances

Taste threshold values

Taste characteristics at 1 to 5 ppm: sulfureous, vegetative tomato, sweet, creamed corn, corn and asparagus with a dairy creaminess and a slight minty afternote, alliaceous.

General Description

A clear colorless to straw colored liquid with a disagreeable odor. Flash point less than 0°F. Less dense than water and slightly soluble in water. Vapors are heavier than air.

Air & Water Reactions

Highly flammable. Slightly soluble in water.

Reactivity Profile

Organosulfides, such as Dimethyl sulfide, are incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. Many of these compounds may liberate hydrogen sulfide upon decomposition or reaction with an acid. Dimethyl sulfide rapidly decomposes dibenzoyl peroxide explosively in the absence of solvent, [J. Org. Chem., 1972, 37, 2885]. The sulfide also decomposes xenon difluoride explosively at ambient temps, [J, Chem Soc., 1984, 2827]. Interaction of Dimethyl sulfide and oxygen is explosive at 210°C and above, [Atmos. Environ., 1967, 1, 491-497]. A delayed explosion occurred in a system containing nitric acid, Dimethyl sulfide, and 1, 4-dioxane, even with cooling with liquid nitrogen, [Chem. Abs., 1972, 76, 13515].

Health Hazard

Inhalation causes moderate irritation of upper respiratory system. Contact of liquid with eyes causes moderate irritation. Repeated contact with skin may extract oils and result in irritation. Ingestion causes nausea and irritation of mouth and stomach.

Chemical Reactivity

Reactivity with Water : No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

Safety Profile

Poison by inhalation. Moderately toxic by ingestion. A skin and severe eye irritant. A very dangerous fire hazard when exposed to heat or flame. Explosive in the form of vapor when exposed to heat or flame. Can react vigorously with oxidizing materials. To fight fire, use CO2, dry chemical. When heated to decomposition it emits highly toxic fumes of SOx and may explode. See also SULFIDES.

Purification Methods

Purify dimethyl sulfide via the Hg(II) chloride complex by dissolving 1 mole of Hg(II)Cl2 in 1250mL of EtOH and slowly adding the boiling alcoholic solution of Me2S to give the right ratio for 2(CH3)2S.3HgCl2. After recrystallisation of the complex to constant melting point, 500g of complex is heated with 250mL conc HCl in 750mL of water. The sulfide is separated, washed with water, and dried with CaCl2 and CaSO4. Finally, it is distilled under reduced pressure from sodium. Precautions should be taken (efficient fume hood) because of its very UNPLEASANT ODOUR.[Beilstein 1 IV 1275.]

Raw materials

Dimethyl sulfate-->Carbon disulphide-->Aluminum oxide-->HYDROGEN SULFIDE-->Sodium thiomethoxide-->LIGNIN, ALKALI-->ANION STANDARD - SULFATE

Preparation Products

Dimethyl sulfoxide-->Dimethoate-->3-FURANMETHANOL-->ETHYL 3-FUROATE-->Parathion-methyl-->Ketorolac-->O,O-Dimethyl S-methylcarbamoylmethyl phosphorothioate-->Malathion-->Fluorescent Brightener 185-->Ethyl 5-[3-(4,6-dimethoxy pyrimidyl-2-yl)ureido]methylpyrazolyl-4-carboxylic ester-->Pazufloxacin-->Fenitrothion-->Methidathion-->Orthene-->Fipronil-->FENOTHIOCARB-->Phosmet-->4-AMINO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER-->Dimethylphosphorodithioate-->Dimethyl chlorothiophosphate-->ISOFENPHOS-->CYANOPHOS-->5-HYDROXYMETHYLCYTOSINE-->Azamethiphos-->WL 108477-->CARBOPHENOTHION-->4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXYLIC ACID-->4-AMINO-2-(METHYLTHIO)-6-PYRIMIDINOL-->Ranitidine hydrochloride-->Aminoguanidinium sulphate-->Mifepristone-->5-CARBOXYCYTOSINE-->Methyl [(dimethoxyphosphinothioyl)thio]acetate-->FLOSEQUINAN-->Procarbazone sodium-->Fluticasone propionate-->Ammonium O,O-dimethyl dithiophosphate-->CHLOROMETHYL METHYL SULFIDE-->4-Methylthio-4-methyl-2-pentanone