2,5-Dimethyl Pyrazine

Product Name:

2,5-Dimethyl pyrazine

Synonyms:

tomfor;2,5-Dimethylpyrazine 98+%;2,5-Dimethylprazin;2,5-Dimethylpyrazine (contains 2,6-isomer);2,5-DIMETHYL PYRAZINE, NATURAL;2,5-Dimethylpyrazine,99%;2,5-Dimethylpyrazine, Research grade;2,5-Dimethyl pyrazine >=99.0%

CAS:

123-32-0

MF:

C6H8N2

MW:

108.14

EINECS:

204-618-3

Product Categories:

Pyrazine;Heterocyclic Compounds;Acipimox;Mono- & Polyalkylpyrazines;pyrazine Flavor;Building Blocks;Heterocyclic Building Blocks;Alphabetical Listings;C-D;Flavors and Fragrances;Pyrazine compounds;Pyrazines

Mol File:

123-32-0.mol

Melting point 

15°C

Boiling point 

155 °C(lit.)

density 

0.99 g/mL at 25 °C(lit.)

FEMA 

3272 | 2,5-DIMETHYLPYRAZINE

refractive index 

n20/D 1.502(lit.)

Fp 

147 °F

storage temp. 

Store below +30°C.

form 

Liquid

pka

2.21±0.10(Predicted)

Specific Gravity

0.990

color 

Clear colorless to pale yellow

PH

7 (H2O)

Sensitive 

Hygroscopic

JECFA Number

766

BRN 

107052

CAS DataBase Reference

123-32-0(CAS DataBase Reference)

NIST Chemistry Reference

Pyrazine, 2,5-dimethyl-(123-32-0)

EPA Substance Registry System

Pyrazine, 2,5-dimethyl- (123-32-0)

Hazard Codes 

Xn,Xi

Risk Statements 

22-36/37/38-R22

Safety Statements 

26-36

RIDADR 

NA 1993 / PGIII

WGK Germany 

3

RTECS 

UQ2800000

Hazard Note 

Irritant

TSCA 

Yes

HS Code 

29339990

Chemical Properties

clear colorless to pale yellow liquid

Chemical Properties

2,5-Dimethylpyrazine has a characteristic odor of earthy, potato-like odor.

Uses

2,5-Dimethyl pyrazine is used for blending food, nuts and beverage flavors.

Preparation

By the interaction of acrolein and ammonia when heated in glycerol in the presence of ammonium salts; by self-condensation of aminoacetone, followed by oxidation with mercury chloride.

Aroma threshold values

Detection: 80 ppb to 1.8 ppm

Taste threshold values

Taste characteristics at 7.5 ppm: musty, potato, cocoa and nutty with a fatty and oily nuance

Safety Profile

Moderately toxic by ingestion and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx

Purification Methods

Purify it via its picrate (m 150o) which is decomposed with a base (e,g, KOH) and distilled. [Wiggins and Wise J Chem Soc 4780 1956]. [Beilstein 23/5 V 403.]

Raw materials

Acrolein

Preparation Products

trans-2,5-Dimethylpiperazine-->2,6-Dimethylpyrazine